The Innovations and Discoveries

2018 – 2022

Gabrb3 endothelial cell-specific knockout mice display abnormal blood flow, hypertension, and behavioral dysfunction. Agrud A, Subburaju S, Goel P, Ren J, Kumar AS, Caldarone BA, Dai W, Chavez J, Fukumura D, Jain RK, Kloner RA, Vasudevan A.  Scientific Reports, 2022 Mar 22; 12:4922. PMID: 35318369

Human forebrain endothelial cell therapy for psychiatric disorders. Datta D, Subburaju S, Kaye S, Baruah J, Choi YK, Nian Y, Khalili JS, Chung S, Elkhal A, Vasudevan A.  Molecular Psychiatry, 2021 Sep;26(9):4864-4883. PMID: 32661257

NAD+ mediated rescue of prenatal forebrain angiogenesis restores postnatal behavior. Subburaju S, Kaye S, Choi YK, Baruah J, Datta D, Ren J, Kumar AS, Szabo G, Fukumura D, Jain RK, Elkhal A, Vasudevan A.  Science Advances, 2020 Oct 9; 6:eabb9766. PMID: 33036972

Migration, chemo-attraction and co-culture assays for human stem cell-derived endothelial cells and GABAergic neurons.  Datta D, Vasudevan A.  Journal of Visualized Experiments, 2020 Jan 23; 155. PMID: 32065131

Vascular integrity and signaling determining brain development, network excitability and epileptogenesis. Baruah J, Vasudevan A, Köhling R.  Frontiers in Physiology, 2020 Jan 22; 10:1583. PMID: 32038280

Mechanistic insights into autocrine and paracrine roles of endothelial GABA signaling in the embryonic forebrain. Choi YK, Vasudevan A.  Scientific Reports, 2019 Nov 7; 9(1):16256. PMID: 31700116

The vessels shaping mental health or illness. Baruah J, Vasudevan A.  Open Neurology Journal, 2019 Feb 15; 13:1-9. PMID: 30984305

Endothelial GABA signaling: a phoenix awakened.  Choi YK, Vasudevan A.  Aging, 2018 May 22; 10(5):859-860. PMID: 29846173

Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior.  Li S, Kumar T P, Joshee S, Kirschstein T, Subburaju S, Khalili JS, Kloepper J, Du C, Elkhal A, Szabó G, Jain RK, Köhling R, Vasudevan A.  Cell Research-Nature, 2018 Feb; 28(2):221-248. PMID: 29086765

Mast cells regulate CD4+ T-cell differentiation in the absence of antigen presentation.  Rodriguez Cetina Biefer H, Heinbokel T, Uehara H, Camacho V, Minami K, Nian Y, Koduru S, El Fatimy R, Ghiran I, Trachtenberg AJ, de la Fuente MA, Azuma H, Akbari O, Tullius SG, Vasudevan A, Elkhal A.  Journal of Allergy and Clinical Immunology, 2018 Feb 20. PMID: 29470999

2013 – 2017

Aspects of Tryptophan and Nicotinamide Adenine Dinucleotide in Immunity: A New Twist in an Old Tale. Rodriguez Cetina Biefer H, Vasudevan A, Elkhal A.  International Journal of Tryptophan Research, 2017; 10:1178646917713491. PMID: 28659716

NAD+ protects against EAE by regulating CD4+ T-cell differentiation.  Tullius SG, Biefer HR, Li S, Trachtenberg AJ, Edtinger K, Quante M, Krenzien F, Uehara H, Yang X, Kissick HT, Kuo WP, Ghiran I, de la Fuente MA, Arredouani MS, Camacho V, Tigges JC, Toxavidis V, El Fatimy R, Smith BD, Vasudevan A, ElKhal A.  Nature Communications, 2014 Oct 07; 5:5101. PMID: 25290058

Mesencephalic GABA neuronal development: no more on the other side of oblivion.  Li S, Joshee S, Vasudevan A.  Biomolecular Concepts, 2014 Oct; 5(5):371-82. PMID: 25367618

Efficient specification of interneurons from human pluripotent stem cells by dorsoventral and rostrocaudal modulation. Efficient specification of interneurons from human pluripotent stem cells by dorsoventral and rostrocaudal modulation.  Kim TG, Yao R, Monnell T, Cho JH, Vasudevan A, Koh A, Kumar T P, Moon M, Datta D, Bolshakov VY, Kim KS, Chung S.  Stem Cells, 2014 Jul; 32(7):1789-804. PMID: 24648391

Bidirectional crosstalk between periventricular endothelial cells and neural progenitor cells promotes the formation of a neurovascular unit.  Vissapragada R, Contreras MA, da Silva CG, Kumar VA, Ochoa A, Vasudevan A, Selim MH, Ferran C, Thomas AJ.  Brain Research, 2014 May 27; 1565:8-17. PMID: 24675025

Isolation and culture of endothelial cells from the embryonic forebrain.  Kumar T P, Vasudevan A.  Journal of Visualized Experiments, 2014 Jan 23; (83):e51021. PMID: 24513848

Endothelial VEGF sculpts cortical cytoarchitecture.  Li S, Haigh K, Haigh JJ, Vasudevan A.  The Journal of Neuroscience, 2013 Sep 11; 33(37):14809-15. PMID: 24027281

Autonomous vascular networks synchronize GABA neuron migration in the embryonic forebrain.  Won C, Lin Z, Kumar T P, Li S, Ding L, Elkhal A, Szabó G, Vasudevan A.  Nature Communications, 2013; 4:2149. PMID: 23857367

2008 – 2012

Dopaminergic neurons modulate GABA neuron migration in the embryonic midbrain.  Vasudevan A, Won C, Li S, Erdélyi F, Szabó G, Kim KS.  Development, 2012 Sep; 139(17):3136-41. PMID: 22872083

Basement membrane protein nidogen-1 shapes hippocampal synaptic plasticity and excitability.  Vasudevan A, Ho MS, Weiergräber M, Nischt R, Schneider T, Lie A, Smyth N, Köhling R.  Hippocampus, 2010 May; 20(5):608-20. PMID: 19530222

Angiogenesis in the central nervous system.  Vasudevan A. Letter from the guest editor. Cell Adhesion and Migration, 2009 Apr-Jun; 3(2):198. PMID: 19398894

Angiogenesis in the embryonic CNS: a new twist on an old tale.  Vasudevan A, Bhide PG.  Cell Adhesion and Migration, 2008 Jul-Sep; 2(3):167-9. PMID: 19262109

Compartment-specific transcription factors orchestrate angiogenesis gradients in the embryonic brain.  Vasudevan A, Long JE, Crandall JE, Rubenstein JL, Bhide PG. Nature Neuroscience, 2008 Apr; 11(4):429-39. PMID: 18344991